5-Amino-1MQ

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule research compound supplied in oral capsule format for laboratory and professional reference use. It is studied in the metabolic-research literature as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme expressed in adipose and other metabolically active tissues. This material is a research compound and is not approved by the FDA for therapeutic use; it is provided to licensed practitioners for research and professional reference only. Within the broader field of metabolic and body-composition research, 5-Amino-1MQ is of interest to investigators examining cellular energy regulation, NAD+ biology, and adipocyte function. Any effects described in the literature are observational research findings, and individual results vary.

• Investigated in preclinical literature as a tool compound for studying nicotinamide N-methyltransferase (NNMT) inhibition
• Studied in metabolic research for its reported influence on cellular NAD+ pools and energy metabolism, with the understanding that individual results vary
• Examined in research models exploring adipocyte (fat cell) metabolism and lipid handling
• Of research interest in the context of metabolic-rate and body-composition investigation, with the understanding that individual results vary
• Referenced in exploratory literature on age-related metabolic decline and mitochondrial-related pathways

Oral capsule formats are typically supplied ready for storage without reconstitution; where a lyophilized or powder research format is provided, reconstitution with bacteriostatic water is a common laboratory reference approach. Store sealed product in a cool, dry environment away from direct light and heat; many facilities keep capsules at controlled room temperature and refrigerate any reconstituted or solubilized material, keeping it protected from light. Keep all material clearly labeled, secured, and out of reach of unauthorized persons. All clinical protocols, including any decision on use, dosing, and administration, are determined solely by the licensed ordering provider at their own professional discretion; this is reference information only and is not medical advice.

A per-lot Certificate of Analysis, HPLC purity profile, and mass-spectrometry verification are available on request for this product. Ask your account manager for the current lot documentation.

In the research literature, 5-Amino-1MQ is described as a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that catalyzes the methylation of nicotinamide. By inhibiting NNMT, the compound is proposed in preclinical studies to reduce consumption of methyl-donor and nicotinamide substrates, which researchers hypothesize may influence intracellular NAD+ availability and downstream energy-metabolism signaling in adipose and other tissues. This is a studied, proposed mechanism drawn from laboratory models; it is not an established clinical effect, and outcomes reported in the literature vary between models and conditions.