GHK-Cu

GHK-Cu is a copper-binding tripeptide (glycyl-L-histidyl-L-lysine complexed with copper(II)) supplied here in injectable form as a research-grade compound for licensed-practitioner and laboratory use. The peptide occurs naturally in human plasma and other tissues, and its presence has been examined in the context of age-associated changes; it has been a longstanding subject of investigation in skin biology, extracellular matrix, and tissue-repair research. This material is provided for research and professional use only and is not approved by the FDA for therapeutic use. It is intended as a professional reference item within the Healing and Recovery catalog category, not as a consumer product or a substitute for any approved therapy. Individual results vary, and nothing here should be read as a therapeutic or outcome claim.

• Investigated in preclinical and in vitro literature in connection with skin and connective-tissue repair processes, including collagen and extracellular-matrix dynamics (individual results vary)
• Studied in research settings for reported influence on dermal remodeling, skin-texture appearance, and fibroblast activity in culture (individual results vary)
• Examined in laboratory models in the context of angiogenesis and wound-environment signaling (individual results vary)
• Reported in research to interact with antioxidant and copper-homeostasis pathways relevant to tissue biology (individual results vary)
• Explored in the scientific literature within the broad context of healing, recovery, and age-associated changes in matrix proteins (individual results vary)

Reference handling information for licensed professionals: lyophilized GHK-Cu is typically reconstituted with bacteriostatic water for injection or another sterile diluent appropriate to the laboratory protocol; the copper complex characteristically yields a blue-tinted solution. Store the sealed lyophilized vial cold, generally refrigerated at approximately 2 to 8 degrees C, and for longer-term storage many facilities hold it frozen; protect from light and heat, and avoid repeated freeze-thaw cycles. Once reconstituted, keep refrigerated, protect from light, use within the validated window for the facility, and handle under aseptic technique. Inspect solutions before use and discard if cloudiness, particulates, or discoloration beyond the expected tint are observed. All clinical and research protocols, including any dosing, dilution, and route decisions, are determined solely by the licensed ordering provider; this is reference information for research and professional use only and is not medical advice.

A per-lot Certificate of Analysis, HPLC purity profile, and mass-spectrometry verification are available on request for this product. Ask your account manager for the current lot documentation.

In published research, GHK-Cu is described as a copper-carrier tripeptide whose proposed activity is generally attributed to its affinity for copper(II) ions and to the delivery and exchange of copper within biological systems. Investigators have reported that the peptide-copper complex may influence the expression of genes associated with extracellular-matrix synthesis and remodeling, affect fibroblast and keratinocyte behavior in culture, and participate in signaling related to wound environments and antioxidant defense. These mechanisms are described as studied or proposed in preclinical and in vitro literature rather than as established clinical effects, and individual results vary.