HCG

HCG (human chorionic gonadotropin) is a glycoprotein hormone composed of an alpha subunit shared with other gonadotropins and a hormone-specific beta subunit. It is supplied here as a lyophilized powder for reconstitution, intended for research and professional use only and not approved by the FDA for therapeutic use. Within the Growth Hormone & Performance category, HCG is of interest in the scientific literature primarily for its structural and functional resemblance to luteinizing hormone (LH) and its activity at the LH/CG receptor. This reference entry is intended for licensed practitioners evaluating the compound in a research or professional context and is not for patient-facing promotion. General areas of research interest described in the literature include reproductive endocrinology, gonadal axis signaling, and investigations of endogenous steroidogenic pathways. Individual results vary, and the descriptions here reflect reported research interest rather than established therapeutic effects.

• Investigated in reproductive endocrinology literature as a luteinizing-hormone analog acting at the LH/CG receptor
• Studied in research models in the context of endogenous testosterone-pathway signaling along the hypothalamic-pituitary-gonadal axis; individual results vary
• Examined in preclinical and clinical research literature in the context of ovulation and corpus luteum function
• Referenced in performance and recovery research as a tool for studying gonadal steroidogenesis; individual results vary
• Used as a reference ligand in laboratory investigations of gonadotropin receptor binding and downstream signaling

Supplied as a lyophilized powder. Reference handling: reconstitute with bacteriostatic water (or another laboratory-appropriate diluent) by adding the diluent slowly against the vial wall and swirling gently rather than shaking, until fully dissolved. Store the unopened lyophilized vial as labeled, typically refrigerated, and keep it protected from light and excess heat; the reconstituted solution is generally kept refrigerated and protected from light, with attention to product-specific stability windows. Avoid repeated freeze-thaw cycles and do not use if the solution is cloudy or contains particulates. This compound is provided for research and professional use only and is not approved by the FDA for therapeutic use. All clinical protocols, including any decisions regarding preparation, concentration, and use, are determined solely by the licensed ordering provider; this is reference information only and not medical advice.

A per-lot Certificate of Analysis, HPLC purity profile, and mass-spectrometry verification are available on request for this product. Ask your account manager for the current lot documentation.

HCG is reported in the research literature to act as an agonist at the luteinizing hormone/chorionic gonadotropin (LH/CG) receptor, a G-protein-coupled receptor expressed on Leydig cells in the testes and on theca and granulosa cells in the ovaries. Because its beta subunit confers structural similarity to LH, studies describe HCG as mimicking LH signaling, with receptor activation proposed to stimulate adenylate cyclase, raise intracellular cAMP, and thereby modulate steroidogenic enzyme activity and gonadal steroid output in experimental models. Individual results vary, and these mechanistic descriptions reflect proposed and studied pathways rather than confirmed therapeutic effects.