Selank

Selank is a synthetic heptapeptide analog of the endogenous immunomodulatory peptide tuftsin, originally characterized in Russian peptide research literature. In its injectable presentation it is supplied as a lyophilized powder for reconstitution and is offered here strictly as a research compound for laboratory and professional reference use. Selank is not approved by the FDA for therapeutic use, and nothing in this listing should be read as a therapeutic, diagnostic, or treatment claim.

Within the Cognitive and Longevity category, Selank is of interest to investigators examining short regulatory peptides and their relationship to neuromodulatory and stress-adaptation pathways. This entry is intended as professional reference information for licensed practitioners evaluating the compound; it does not characterize patient outcomes, and individual results vary.

• Investigated in preclinical literature for its relationship to anxiety-related and stress-adaptation behavioral models (individual results vary)
• Studied in research settings for possible relationships to attention, learning, and memory-associated endpoints (individual results vary)
• Examined in the literature for proposed interactions with monoaminergic and GABAergic signaling pathways (individual results vary)
• Reported in research literature to be of interest for its proposed immunomodulatory activity as a tuftsin analog (individual results vary)
• Explored in studies for its relationship to brain-derived neurotrophic factor (BDNF) expression and related neuroplasticity markers (individual results vary)

Reference handling information only: the lyophilized peptide is typically reconstituted with bacteriostatic water or another suitable sterile diluent per the laboratory's standard practice. Before reconstitution, store the sealed vial frozen or refrigerated and protect it from light, heat, and moisture, and minimize freeze-thaw cycles. After reconstitution, keep refrigerated, protect from light, and handle using aseptic technique. Inspect the solution for clarity prior to use and discard if particulates or discoloration are observed. This compound is provided for research and professional use and is not approved by the FDA for therapeutic use. No dosing, frequency, or administration protocol is provided here; all clinical protocols and handling decisions are determined solely by the licensed ordering provider, and this is reference information only, not medical advice.

A per-lot Certificate of Analysis, HPLC purity profile, and mass-spectrometry verification are available on request for this product. Ask your account manager for the current lot documentation.

As a synthetic analog of the tuftsin fragment, Selank is proposed in the research literature to engage neuromodulatory systems rather than a single receptor target. Investigators have described possible influences on the balance of monoamine and GABAergic neurotransmission, proposed modulation of enkephalin-degrading enzyme activity that may relate to the persistence of endogenous regulatory peptide signaling, and associations with the expression of neurotrophic factors such as BDNF. Its peptide structure has also been studied for relative resistance to rapid enzymatic breakdown compared with native tuftsin. These mechanisms are proposed or studied in preclinical models only, have not been established for any clinical use, and individual results vary.