Description
TB-500 is a synthetic peptide corresponding to a bioactive fragment of Thymosin Beta-4, a naturally occurring protein expressed in many cell types and tissues. The fragment is associated with the actin-binding region of the parent protein and is supplied here in lyophilized form for licensed-practitioner ordering. Within the Healing & Recovery category, it is among the peptides cited in preclinical and exploratory tissue-repair literature. This product is intended for research and professional use only and is not approved by the FDA for therapeutic use. It is offered as a wholesale catalog reference item for qualified ordering providers; any application is determined solely at the discretion of the licensed practitioner. Individual results vary.
Reported research uses
- Investigated in preclinical literature for its proposed role in actin regulation and cell migration within tissue-repair research models; individual results vary
- Studied in research models in connection with soft-tissue, tendon, and ligament recovery dynamics; individual results vary
- Examined in exploratory studies for angiogenesis and microvascular response; individual results vary
- Reported in research settings in connection with inflammatory modulation and extracellular matrix remodeling; individual results vary
- Referenced in animal-model literature exploring wound-healing and recovery dynamics; individual results vary
Dosing & handling
Supplied as a lyophilized powder for research handling. Typical reference practice is reconstitution with bacteriostatic water or another suitable sterile diluent per laboratory standard, adding the diluent slowly against the vial wall and gently swirling rather than shaking to help preserve peptide integrity. Store unreconstituted vials in a cool, dry place away from light; common reference practice is refrigeration and, for longer holding, freezing of the sealed lyophilized product. After reconstitution, keep refrigerated, protect from light and excess heat, and use within the working window indicated by your laboratory's stability standards. Avoid repeated freeze-thaw cycles and inspect solution clarity before use. This is reconstitution, storage, and handling reference information only; all clinical and research protocols, including any dosing, are determined solely by the licensed ordering provider, and this is not medical advice.
COA / HPLC / MS
A per-lot Certificate of Analysis, HPLC purity profile, and mass-spectrometry verification are available on request for this product. Ask your account manager for the current lot documentation.
Mechanism of action
As a fragment of Thymosin Beta-4, TB-500 is studied for its proposed ability to bind G-actin and influence actin sequestration and polymerization, processes associated in the literature with cytoskeletal organization and cell motility. Preclinical research has explored how this proposed actin-modulating activity may relate to cell migration, angiogenesis, and extracellular matrix interactions observed in tissue-repair research models. The proposed mechanisms remain under investigation and are characterized in the research setting rather than established clinically; individual results vary.